{"id":1,"date":"2025-10-28T15:05:05","date_gmt":"2025-10-28T15:05:05","guid":{"rendered":"https:\/\/mvminstitute.edu.in\/mvm-college-of-allied-health-science\/?p=1"},"modified":"2025-11-03T16:35:59","modified_gmt":"2025-11-03T16:35:59","slug":"hello-world","status":"publish","type":"post","link":"https:\/\/mvminstitute.edu.in\/mvm-college-of-allied-health-science\/2025\/10\/28\/hello-world\/","title":{"rendered":"STUDY OF HAEMATOLOGICAL PARAMETERS IN MALARIA"},"content":{"rendered":"\n<figure class=\"wp-block-table\"><table class=\"has-fixed-layout\"><tbody><tr><td>2024-02-28 By Rashmi<\/td><td><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n<h4>ABSTRACT<\/h4>\n<p>Malaria causing plasmodia are parasites of blood and hence induce haematological alterations. The haematological changes that have been reported to accompany malaria include anemia, thrombocytopenia and leucocytosis, leukopenia, mild to moderate atypical lymphocytosis, monocytosis, eosinophilia and neutrophilia.<\/p>\n<h4>INTRODUCTION<\/h4>\n<p>Malaria is a major health problem in India, being one of the biggest burdens in terms of morbidity and mortality among all infectious diseases. More than 100 countries in the world are considered malarious, and more than 2.4 billion of the world\u2019s population is at risk. The worldwide annual incidence of malaria is estimated to be about 300-500 million cases. Malaria kills between 1.1 and 2.7 million people annually of which majority are children under five years.<br \/>Malaria causing plasmodia are parasites of blood and hence induce hematological alterations. The hematological changes that have been reported to accompany malaria include anemia, thrombocytopenia and leucocytosis, leucopenia, mild to moderate atypical lymphocytosis, monocytosis, eosinophilia and neutrophilia.3-8 Platelet abnormalities are both qualitative as well as quantitative<br \/>Thrombocytopenia is common occurrence in acute malaria and it is observed in vivax and falciparum malaria to varying degrees. Hepatic involvement in P. falciparum malaria is not an uncommon presentation and presence of jaundice (bilirubin &gt;3mg\/dl) is one of the indicators of severe malaria as defined by the WHO.<\/p>\n<h4>NEED OF THE STUDY<\/h4>\n<p>Various haematological findings can help in early diagnosis of malaria which is essential for timely and appropriate treatment which can limit the morbidity and prevent further complications.<\/p>\n<h4>OBJECTIVE<\/h4>\n<p>Malaria is transmitted by the female anopheles mosquito, causes clinical illness and pathological changes in various body organs with the parasites invading and multiplying in the circulating red blood cells. Malaria causes numerous hematological alterations of which anemia and thrombocytopenia are the most important.<br \/>Fever is most common symptom. Also chills and rigor, nausea and vomiting, headache are still the common symptoms of malaria. Even though malaria is commonly associated with thrombocytopenia, rash and petechial hemorrhages in the skin or mucous membranes are not the common presentation features.<\/p>\n<h4>METHODS<\/h4>\n<p>Following readings were noted<\/p>\n<ul>\n<li><i class=\"fa-sharp fa-regular fa-square-check\"><\/i>\u00a0Hemoglobin (HB%)<\/li>\n<li><i class=\"fa-sharp fa-regular fa-square-check\"><\/i>\u00a0HCT<\/li>\n<li><i class=\"fa-sharp fa-regular fa-square-check\"><\/i>\u00a0Total leukocyte count (TLC)<\/li>\n<li><i class=\"fa-sharp fa-regular fa-square-check\"><\/i>\u00a0Differential leukocyte<\/li>\n<li><i class=\"fa-sharp fa-regular fa-square-check\"><\/i>\u00a0Platelet count.<\/li>\n<\/ul>\n<h4>BIOCHEMICAL INVESTIGATION<\/h4>\n<p>Liver function test (LFT): The patient\u2019s samples were processed for Liver function tests including-Serum Bilirubin, AST, ALT<br \/>Kidney function test (KFT):The patient\u2019s samples were processed for Kidney function tests including-Serum creatinine and blood urea<\/p>\n<h4>PERIPHERAL BLOOD SMEAR EXAMINATION<\/h4>\n<p>Peripheral blood smear examination was done systematically under low, high and oil immersion of microscope for<\/p>\n<ul>\n<li><i class=\"fa-sharp fa-regular fa-square-check\"><\/i>\u00a0RBC morphology<\/li>\n<li><i class=\"fa-sharp fa-regular fa-square-check\"><\/i>\u00a0Total leukocyte count and differential count<\/li>\n<li><i class=\"fa-sharp fa-regular fa-square-check\"><\/i>\u00a0Platelet adequacy<\/li>\n<li><i class=\"fa-sharp fa-regular fa-square-check\"><\/i>\u00a0Type of malaria parasite<\/li>\n<\/ul>\n<p>In anemic patients, most commonly RBC\u2019s were Normocytic Normochromic followed by Microcytic Hypochromic. Microcytic Hypochromic blood picture was seen nearly equal in both falciparum and vivax infection.<\/p>\n<h4><i>BLOOD COUNT<\/i><br \/>Haemoglobin concentration<\/h4>\n<p>Majority of the patients undergo either mild (40%) or moderate degree (30%) of anemia. Hb Concentration less than 7 gm% and Haematocrit values less than 20 were seen in Falciparum infection.<\/p>\n<h4>Platelet count<\/h4>\n<p>ecreased platelet counts were a constant feature of both types of malaria with less than 1.5 lakhs\/mm. Severe Platelet Reduction Decreased (less than 50,000) can be observed.<\/p>\n<h4>Total leucocyte count (TLC)<\/h4>\n<p>Majority of the patients have normal Total WBC count<\/p>\n<h4>CONCLUSION<\/h4>\n<p>Malaria is one of the most common infections in Indian Subcontinent. Malaria affects mostly adults with male predominance. Fever, Pallor and Splenomegaly are common clinical features in malaria. Malarial infection causes various haematological and biochemical changes.<br \/>Anaemia and thrombocytopenia of varying severity are most frequently observed haematological findings however bleeding manifestations are uncommon.<br \/>In a patient with febrile illness, observation of thrombocytopenia warrants careful search for malaria parasite. P. falciparum is associated with serious complications like Severe anemia, Malarial hepatitis and Renal failure hence P. falciparum infection on suspicion of complication should be further evaluated. Various haematological findings can help in early diagnosis of malaria which is essential for timely and appropriate treatment which can limit the morbidity and prevent further complications.<\/p>","protected":false},"excerpt":{"rendered":"<p>2024-02-28 By Rashmi ABSTRACT Malaria causing plasmodia are parasites of blood and hence induce haematological alterations. The haematological changes that have been reported to accompany malaria include anemia, thrombocytopenia and leucocytosis, leukopenia, mild to moderate atypical lymphocytosis, monocytosis, eosinophilia and neutrophilia. INTRODUCTION Malaria is a major health problem in India, being one of the biggest &hellip; <\/p>\n<p class=\"link-more\"><a href=\"https:\/\/mvminstitute.edu.in\/mvm-college-of-allied-health-science\/2025\/10\/28\/hello-world\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;STUDY OF HAEMATOLOGICAL PARAMETERS IN MALARIA&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":522,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-1","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized","entry"],"acf":[],"_links":{"self":[{"href":"https:\/\/mvminstitute.edu.in\/mvm-college-of-allied-health-science\/wp-json\/wp\/v2\/posts\/1","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mvminstitute.edu.in\/mvm-college-of-allied-health-science\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/mvminstitute.edu.in\/mvm-college-of-allied-health-science\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/mvminstitute.edu.in\/mvm-college-of-allied-health-science\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/mvminstitute.edu.in\/mvm-college-of-allied-health-science\/wp-json\/wp\/v2\/comments?post=1"}],"version-history":[{"count":0,"href":"https:\/\/mvminstitute.edu.in\/mvm-college-of-allied-health-science\/wp-json\/wp\/v2\/posts\/1\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/mvminstitute.edu.in\/mvm-college-of-allied-health-science\/wp-json\/wp\/v2\/media\/522"}],"wp:attachment":[{"href":"https:\/\/mvminstitute.edu.in\/mvm-college-of-allied-health-science\/wp-json\/wp\/v2\/media?parent=1"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/mvminstitute.edu.in\/mvm-college-of-allied-health-science\/wp-json\/wp\/v2\/categories?post=1"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/mvminstitute.edu.in\/mvm-college-of-allied-health-science\/wp-json\/wp\/v2\/tags?post=1"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}